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The influence of therapeutic doses of spironolactone on the liver microsomal enzyme system and digoxin elimination in man [proceedings]

1977; Wiley; Volume: 4; Issue: 5 Linguagem: Inglês

10.1111/j.1365-2125.1977.tb00811.x

1365-2125

Ohnhaus Ee, J Masson,

Cancer therapeutics and mechanisms

British Journal of Clinical PharmacologyVolume 4, Issue 5 p. 639P-640P Free Access The influence of therapeutic doses of spironolactone on the liver microsomal enzyme system and digoxin elimination in man [proceedings] EE Ohnhaus, EE OhnhausSearch for more papers by this authorJP Masson, JP MassonSearch for more papers by this author EE Ohnhaus, EE OhnhausSearch for more papers by this authorJP Masson, JP MassonSearch for more papers by this author First published: October 1977 https://doi.org/10.1111/j.1365-2125.1977.tb00811.xCitations: 5AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. References BACHUR, N.R., EGORIN, M.J., HILDEBRAND, R.C. & TAKANASHI, S. (1973). Human biliary metabolites of adriamycin and daunorubicin. Proc. Am. Ass. Cancer Res., 14, 14. BENJAMIN, R.S., RIGGS, Jr., C.E., SERPICK, A.A. & BACHUR, N.R. (1975). Quantitative human biliary excretion of adriamycin. Proc. Am. Ass. Cancer Res., 16, 127. TAKANASHI, S. & BACHUR, N.R. (1976). Adriamycin metabolism in man: evidence from urinary metabolites. Drug Metab. Dispos., 4, 79– 87. References STRIPP, B., HAMRICK, M.E., ZAMPAGLIONE, N.G. & GILETTE, J.R. (1971). The effect of spironolactone on drug metabolism by hepatic microsomes. J. Pharmac. exp.Ther., 176, 766– 771. TAYLOR, S.A., RAWLINS, M.D. & SMITH, S.E. (1972). Spironolactone—a weak enzyme inducer in man. J. Pharm. Pharmac., 24, 578– 579. WIRTH, K.E. & FRÖHLICH, C. (1974). Effect of spironolactone on excretion of [3H]-digoxin and its metabolites in rats. Eur. J. Pharmac., 29, 43– 51. Citing Literature Volume4, Issue5October 1977Pages 639P-640P ReferencesRelatedInformation