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Medulloblastoma Incidence has not Changed Over Time

2009; Lippincott Williams & Wilkins; Volume: 31; Issue: 12 Linguagem: Inglês

10.1097/mph.0b013e3181bbc502

1536-3678

Sonia Partap, Emily Curran, Jennifer M. Propp, Gem M. Le, Kristin L. Sainani, Paul G. Fisher,

Hedgehog Signaling Pathway Studies

Earlier studies have reported changes in the incidence of medulloblastoma (MB) but have conflicted, likely because of small sample size or misclassification of MB with primitive neuroectodermal tumor (PNET). The incidence of MB and PNET from 1985 to 2002 was determined from the Central Brain Tumor Registry of the United States, a large population-based cancer registry, using strict histologic and site codes. No statistically significant change in MB incidence was observed over the last 2 decades, but there was an increase in MB and PNET combined.