MRI of small human stroke shows reversible diffusion changes in subcortical gray matter
2000; Lippincott Williams & Wilkins; Volume: 11; Issue: 9 Linguagem: Inglês
10.1097/00001756-200006260-00043
ISSN1473-558X
AutoresClaudia A. Doege, Christian Kerskens, Berenice I. Romero, Peter Brunecker, Wolfram von Pannwitz, Jan Jungehülsing, Bianca Müller, Arno Villringer,
Tópico(s)Advanced MRI Techniques and Applications
ResumoSix patients who had suffered small cerebral ischemia affecting subcortical gray matter were examined with diffusion weighted imaging (DWI) and T2-weighted imaging within the first 8 h, during the next 2 days and after 5–16 days. Areas of apparent diffusion coefficient (ADC) decreases were observed acutely and reached the maximum size during the subsequent 2 days. Noticeably, in all subjects, a large portion of the ADC lesion was reversible as judged from the lesion size on final T2 image. The regular reversibility of the ADC decreases in this setting may indicate a hitherto not understood pathophysiological process occurring in small ischemic stroke.
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