Portal de Periódicos da CAPES

T-cell effector mechanisms: γδ and CD1d-restricted subsets

2003; Elsevier BV; Volume: 15; Issue: 3 Linguagem: Inglês

10.1016/s0952-7915(03)00045-1

1879-0372

Julie Jameson, Deborah A. Witherden, Wendy L. Havran,

IL-33, ST2, and ILC Pathways

γδ T lymphocytes and CD1d-restricted natural killer T cells are classified as innate T lymphocytes, which perform effector functions that protect from malignancy and maintain tissue integrity. Innate T cells also play important regulatory roles in autoimmunity, inflammation and infection. Recent advances have established innate T cells as both effectors and regulators of disease in biological models.