Portal de Periódicos da CAPES

Enoxaparin-induced hemorrhagic bullous dermatosis in a leprosy patient

2014; Taylor & Francis; Volume: 34; Issue: 3 Linguagem: Inglês

10.3109/15569527.2014.950381

1556-9535

Savaş Öztürk, İlkay Can, İlker Erden, Hadice Akyol, Özgen Arslan Solmaz,

Autoimmune Bullous Skin Diseases

Enoxaparin is a low-molecular-weight heparin that has been used widely to prevent and treat thromboembolic disorders for at least 30 years. The most common adverse skin reactions to enoxaparin are ecchymosis and skin necrosis due to vasculitis, urticaria, angioedema and erythema. Side effects from heparin administration are rare and usually located at the injection site. However, recent reports have suggested that they can also occur at a distance from the site of injection. Moreover, the etiopathogenesis has not been fully explained. In this article, we present a case of hemorrhagic bullous dermatosis associated with enoxaparin for the treatment of ischemic heart disease that developed in a patient with a past history of lepromatous leprosy.