Artigo Acesso aberto Revisado por pares

JPred: a consensus secondary structure prediction server.

1998; Oxford University Press; Volume: 14; Issue: 10 Linguagem: Inglês

10.1093/bioinformatics/14.10.892

ISSN

1367-4811

Autores

James Cuff, M. Clamp, A.S. Siddiqui, M. Raymond V. Finlay, Geoffrey J. Barton,

Tópico(s)

Protein Structure and Dynamics

Resumo

An interactive protein secondary structure prediction Internet server is presented. The server allows a single sequence or multiple alignment to be submitted, and returns predictions from six secondary structure prediction algorithms that exploit evolutionary information from multiple sequences. A consensus prediction is also returned which improves the average Q3 accuracy of prediction by 1% to 72.9%. The server simplifies the use of current prediction algorithms and allows conservation patterns important to structure and function to be identified.http://barton.ebi.ac.uk/servers/jpred.h tmlgeoff@ebi.ac.uk

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