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Percutaneous absorption of chlorhexidine in neonatal cord care.

1981; BMJ; Volume: 56; Issue: 11 Linguagem: Inglês

10.1136/adc.56.11.878

1468-2044

Peter Aggett, L. V. Cooper, Stuart H. Ellis, J McAinsh,

Neonatal skin health care

The percutaneous absorption of chlorhexidine during its routine use in topical antiseptic preparations used in umbilical cord care was investigated by determining plasma chlorhexidine concentrations at ages 5 and 9 days. These showed that percutaneous absorption of chlorhexidine occurred in preterm neonates treated with a 1% solution of chlorhexidine in ethanol, but not in term infants similarly treated, or in preterm infants treated only with a dusting powder containing 1% chlorhexidine and 3% zinc oxide.