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Corneal Endothelial Polymegathism after the Extended Wear of Rigid Gas-Permeable Contact Lenses

1988; Lippincott Williams & Wilkins; Volume: 65; Issue: 2 Linguagem: Inglês

10.1097/00006324-198802000-00004

1538-9235

Gary Orsborn, JOHN P. SCHOESSLER,

Glaucoma and retinal disorders

To determine if there are any corneal endothelial cell size and shape changes in subjects wearing rigid gas-permeable contact lenses for cosmetic extended wear, six unadapted lens wearers were fitted using four different lens materials. Each subject wore one lens extended-wear and the other daily-wear for 3 months. Before lens wear and after 3 months, noncontact endothelial photographs were taken. Cell tracings were analyzed by a digitizing computer. This study showed significant endothelial polymegathism, an increase in maximum cell area to minimum cell area, and a significant decrease in percent frequency of hexagonal cells in the extended-wear eyes. There existed in these subjects a significant correlation between changes in cell size (polymegathism) and cell shape (pleomorphism).