The biosynthesis of citrinin by Penicillium citrinum
1981; Linguagem: Inglês
10.1039/p19810002577
ISSN2050-8255
AutoresJill Barber, Rachel H. Carter, Mary J. Garson, James Staunton,
Tópico(s)Fungal Biology and Applications
ResumoIncorporation studies have been carried out with [Me-13C]methionine and aromatic compounds labelled with 14C or 2H. Evidence is presented that 4,6-dihydroxy-3,5-dimethyl-2-(1-methyl-2-oxopropyl)benzaldehyde (13) is the first enzyme-free aromatic intermediate in the biosynthesis of citrinin in P. citrinum, and that all three methylations take place on the polyketide synthetase complex.
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