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Long-term outcome of cerebral infarction in young adults

2004; Wiley; Volume: 110; Issue: 2 Linguagem: Inglês

10.1111/j.1600-0404.2004.00273.x

1600-0404

Halvor Næss, Harald Nyland, Lars Thomassen, J. H. Aarseth, K-M Myhr,

Intracranial Aneurysms: Treatment and Complications

Objectives – We analysed the long-term outcome of 232 young adults aged 15–49 years with first-ever cerebral infarction in 1988–1997 in western Norway. Material and methods – Mortality, recurrence, epilepsy, functional state as evaluated by modified Rankin scale (mRS), and employment were analysed at follow-up (mean time 5.7 years). Results – Twenty-three (9.9%) patients had died. Recurrence occurred in 9.9%, and post-stroke seizures developed in 10.5%. Recurrence was associated with diabetes mellitus (P = 0.005). Favourable functional outcome (mRS = 2) was found in 77.9%. The functional outcome was better in posterior than anterior circulation infarctions (P = 0.011). Unfavourable functional outcome (mRS > 2) was associated with diabetes mellitus (P = 0.001) and severity of neurological deficits on admission for the index stroke (P < 0.001). Only 58.3% were employed at follow-up. Conclusion – This population-based study shows that, although the majority had favourable functional outcome, cerebral infarction had major long-term impact on young adults as evaluated by mortality, recurrence and employment status.