Free radical scavenging of Ganoderma lucidum polysaccharides and its effect on antioxidant enzymes and immunity activities in cervical carcinoma rats
2009; Elsevier BV; Volume: 77; Issue: 2 Linguagem: Inglês
10.1016/j.carbpol.2009.01.009
ISSN1879-1344
AutoresXiaoping Chen, Yan Chen, ShuiBing Li, Chen Youguo, Lan JianYun, Liu LanPing,
Tópico(s)Medicinal Plants and Bioactive Compounds
ResumoGanoderma lucidum are used as traditional edible and medicinal materials in China. In this study, antioxidant activities of polysaccharides from G. lucidum in China were investigated. The influence of G. lucidum polysaccharides upon activities of serum antioxidant enzymes and immunity in rats with cervical cancer. The antioxidant activity was measured by DPPH−, O−, and OH− free radicals scavenging. Results showed that G. lucidum polysaccharides exhibited the higher DPPH−, O−, and OH− free radicals scavenging activities. The results still showed that G. lucidum polysaccharides could significantly enhance the antioxidant enzyme activities (SOD, CAT and GPx), and reduce levels of IL-1β, IL-6 and TNF-α in rats with cervical cancer.
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