Artigo Produção Nacional Revisado por pares

Genotoxic effects of the herbicide Roundup Transorb® and its active ingredient glyphosate on the fish Prochilodus lineatus

2014; Elsevier BV; Volume: 37; Issue: 1 Linguagem: Inglês

10.1016/j.etap.2013.12.012

ISSN

1872-7077

Autores

Natália Cestari Moreno, Silvia Helena Sofia, Cláudia Bueno dos Reis Martinez,

Tópico(s)

Pesticide Exposure and Toxicity

Resumo

Roundup Transorb® (RT) is a glyphosate-based herbicide and despite its wide use around the world there are few studies comparing the effects of the active ingredient with the formulated product. In this context the purpose of this study was to compare the genotoxicity of the active ingredient glyphosate with the formulated product RT in order to clarify whether the active ingredient and the surfactant of the RT formula may exert toxic effects on the DNA molecule in juveniles of fish Prochilodus lineatus. Erythrocytes and gill cells of fish exposed to glyphosate and to RT showed DNA damage scores significantly higher than control animals. These results revealed that both glyphosate itself and RT were genotoxic to gill cells and erythrocytes of P. lineatus, suggesting that their use should be carefully monitored considering their potential impact on tropical aquatic biota.

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