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The Effect of Laparoscopic and Open Donor Nephrectomy on the Long-Term Renal Function in Donor and Recipient: A Retrospective Study

2005; Wolters Kluwer; Volume: 80; Issue: 5 Linguagem: Inglês

10.1097/01.tp.0000172219.10178.0d

1534-6080

May Y. Lind, Ingrid Mertens Zur Borg, Eric J. Hazebroek, Wim C.J. Hop, Ian P.J. Alwayn, Willem Weimar, Jan N.M. IJzermans,

Organ Transplantation Techniques and Outcomes

Pneumoperitoneum, as used in laparoscopic donor nephrectomy (LDN), may result in negative effects on renal function in donor and recipient. This study compares long-term serum creatinine in donor and recipient after laparoscopic and open donor nephrectomy (ODN). A retrospective analysis of 120 LDN and 100 ODN donors and their recipients was performed. Serum creatinine of donor and recipient was recorded and analyzed. The follow-up period posttransplantation was 3 years. Serum creatinine in the recipients was significantly higher in the LDN groups the first week after transplantation. Serum creatinine in the donor was significantly higher in the LDN group at 1 day, 3 months, and 1 year posttransplant. Finally, creatinine levels remained 40% higher compared to preoperative values in both donor groups. LDN results in higher short-term serum creatinine levels in donor and recipient. Long-term serum creatinine levels were comparable after LDN or ODN in donor and recipient.