Plasma cell mastitis: A pathologic entity
1939; Elsevier BV; Volume: 43; Issue: 3 Linguagem: Inglês
10.1016/s0002-9610(39)90643-4
ISSN1879-1883
Autores Tópico(s)Neuroendocrine Tumor Research Advances
ResumoA gross and microscopic study was made of plasma cell mastitis of the breast as presented in thirteen cases, including one here reported. Clinically this condition is often confused with cancer, but the history is characteristic. Although the gross features of the tumor are often equivocating, the histology is almost pathognomonic. It is characterized by an inflammatory granulation tissue which presents a preponderance, frequently almost a pure culture, of plasma cells. However, associated with dilated ducts and a desquamative epithelial hyperplasia, it may be confused with comedocarcinoma or its fibroblastic and giant cell formation may suggest tuberculosis. A recent case of multiple plasma cell tumors following an initial plasma cell mastitis of the breast suggests that the entity may be neoplastic after all. At least it should be considered precancerous and treated as such. The rarity of the disease is more apparent than actual, for many cases go unrecognized or unrecorded.
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