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Thalamic tremor: Correlations with three-dimensional magnetic resonance imaging data and pathophysiological mechanisms

2000; Wiley; Volume: 15; Issue: 5 Linguagem: Inglês

10.1002/1531-8257(200009)15

1531-8257

Pierre Krystkowiak, Pascal Martinat, Fran�ois Cassim, J.P. Pruvo, Didier Leys, Jean‐Daniel Guieu, Alain Dest�e, Luc Defebvre,

Neurological and metabolic disorders

Movement DisordersVolume 15, Issue 5 p. 911-918 Article Thalamic tremor: Correlations with three-dimensional magnetic resonance imaging data and pathophysiological mechanisms Pierre Krystkowiak MD, Pierre Krystkowiak MD Departments of Neurology, Neuroradiology, and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorPascal Martinat MD, Pascal Martinat MD Departments of Neurology and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorFrançois Cassim MD, François Cassim MD Department of Neuroradiology and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorJean-Pierre Pruvo MD, Jean-Pierre Pruvo MD Departments of Neurology and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorDidier Leys MD, Didier Leys MD Departments of Neurology, Neuroradiology, and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorJean-Daniel Guieu PhD, Jean-Daniel Guieu PhD Department of Neuroradiology and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorAlain Destée MD, Corresponding Author Alain Destée MD Departments of Neurology, Neuroradiology, and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceClinique Neurologique, CHRU de Lille Hôpital R. Salengro, 59037 Lille Cedex, FranceSearch for more papers by this authorLuc Defebvre MD, PhD, Luc Defebvre MD, PhD Departments of Neurology, Neuroradiology, and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this author Pierre Krystkowiak MD, Pierre Krystkowiak MD Departments of Neurology, Neuroradiology, and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorPascal Martinat MD, Pascal Martinat MD Departments of Neurology and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorFrançois Cassim MD, François Cassim MD Department of Neuroradiology and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorJean-Pierre Pruvo MD, Jean-Pierre Pruvo MD Departments of Neurology and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorDidier Leys MD, Didier Leys MD Departments of Neurology, Neuroradiology, and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorJean-Daniel Guieu PhD, Jean-Daniel Guieu PhD Department of Neuroradiology and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this authorAlain Destée MD, Corresponding Author Alain Destée MD Departments of Neurology, Neuroradiology, and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceClinique Neurologique, CHRU de Lille Hôpital R. Salengro, 59037 Lille Cedex, FranceSearch for more papers by this authorLuc Defebvre MD, PhD, Luc Defebvre MD, PhD Departments of Neurology, Neuroradiology, and Clinical Neurophysiology, CHRU de Lille, Hôpital Roger Salengro, Lille, FranceSearch for more papers by this author First published: 23 January 2001 https://doi.org/10.1002/1531-8257(200009)15:5 3.0.CO;2-BCitations: 18AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Tremor associated with a single focal thalamic lesion has rarely been reported. Furthermore, the exact localization of the lesions is difficult to determine because of the imprecision of "conventional" radiology (computed tomography scan and/or "standard" magnetic resonance imaging). The aim of this study was to identify which thalamic structures are involved in tremor associated with a single focal thalamic lesion. We selected two patients who presented with unilateral postural and kinetic tremor of the upper limb related to a localized thalamic infarction. Three-dimensional T1-weighted magnetic resonance imaging sequence (MP-RAGE sequence) was used to determine the precise topography of the lesions by stereotactic analysis using the atlas of Hassler. The lesions were located within the pulvinar, the sensory nuclei, the mediodorsal nucleus, and the ventral lateral posterior nucleus (according to the classification of Hirai and Jones), the latter including the ventral intermediate nucleus (Vim according to the classification of Hassler). 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