On the Mechanism by Which Saxitoxin Binds to and Blocks Sodium Channels a
1986; Wiley; Volume: 479; Issue: 1 Linguagem: Inglês
10.1111/j.1749-6632.1986.tb15564.x
ISSN1749-6632
AutoresGary R. Strichartz, Thomas A. Rando, Sherwood Hall, Jane Gitschier, Linda M. Hall, B Magnani, CHRISTINA HANSEN BAY,
Tópico(s)Receptor Mechanisms and Signaling
ResumoAnnals of the New York Academy of SciencesVolume 479, Issue 1 p. 96-112 On the Mechanism by Which Saxitoxin Binds to and Blocks Sodium Channelsa GARY STRICHARTZ, GARY STRICHARTZ Anesthesia Research Laboratories Brigham and Women's Hospital Boston, Massachusetts 02115 Department of Pharmacology Harvard Medical School Boston, Massachusetts 02115Search for more papers by this authorTHOMAS RANDO, THOMAS RANDO Anesthesia Research Laboratories Brigham and Women's Hospital Boston, Massachusetts 02115Search for more papers by this authorSHERWOOD HALL, SHERWOOD HALL Food and Drug Administration Washington, D. C. 20204Search for more papers by this authorJANE GITSCHIER, JANE GITSCHIER Department of Medicine and Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, Calif. 94143.Search for more papers by this authorLINDA HALL, LINDA HALL Department of Genetics Albert Einstein College of Medicine Bronx, New York 10461Search for more papers by this authorBARBARAJEAN MAGNANI, BARBARAJEAN MAGNANI Anesthesia Research Laboratories Brigham and Women's Hospital Boston, Massachusetts 02115Search for more papers by this authorCHRISTINA HANSEN BAY, CHRISTINA HANSEN BAY Anesthesia Research Laboratories Brigham and Women's Hospital Boston, Massachusetts 02115Search for more papers by this author GARY STRICHARTZ, GARY STRICHARTZ Anesthesia Research Laboratories Brigham and Women's Hospital Boston, Massachusetts 02115 Department of Pharmacology Harvard Medical School Boston, Massachusetts 02115Search for more papers by this authorTHOMAS RANDO, THOMAS RANDO Anesthesia Research Laboratories Brigham and Women's Hospital Boston, Massachusetts 02115Search for more papers by this authorSHERWOOD HALL, SHERWOOD HALL Food and Drug Administration Washington, D. C. 20204Search for more papers by this authorJANE GITSCHIER, JANE GITSCHIER Department of Medicine and Howard Hughes Medical Institute, University of California at San Francisco, San Francisco, Calif. 94143.Search for more papers by this authorLINDA HALL, LINDA HALL Department of Genetics Albert Einstein College of Medicine Bronx, New York 10461Search for more papers by this authorBARBARAJEAN MAGNANI, BARBARAJEAN MAGNANI Anesthesia Research Laboratories Brigham and Women's Hospital Boston, Massachusetts 02115Search for more papers by this authorCHRISTINA HANSEN BAY, CHRISTINA HANSEN BAY Anesthesia Research Laboratories Brigham and Women's Hospital Boston, Massachusetts 02115Search for more papers by this author First published: December 1986 https://doi.org/10.1111/j.1749-6632.1986.tb15564.xCitations: 43 a Much of the research reported here was supported by grants from the USPHS (NS 12828 and NS 18467 to GS, and NS 13881 to LH). T. Rando holds a National Service Award (2T 32 GM07753-06) from NIGMS. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Ritchie, J. M., R. B. Rogart & G. R. Strichartz. 1976. J. Physiol. (London) 261: 477–494. 2 Strichartz, G. R. & C. M. HANSEN Bay. 1981. J. Gen. Physiol. 77: 205–221. 3 Strichartz, G. 1982. Mol. Pharmacol. 21: 343–350. 4 Gitschier, J., L. T. Hall & G. R. Strichartz. 1980. Biochim. Biophys. Acta 595: 291–312. 5 Strichartz, G. R., S. Hall & Y. Shimizu. 1984. Biophys. J. 45: 286a. 6 Hansen Bay, C. 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