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Complications of Falciparum Malaria and Their Treatment

1967; American College of Physicians; Volume: 66; Issue: 4 Linguagem: Inglês

10.7326/0003-4819-66-4-807

1539-3704

Thomas W. Sheehy, Richard C. Reba,

Malaria Research and Control

Editorials1 April 1967Complications of Falciparum Malaria and Their TreatmentTHOMAS W. SHEEHY, RICHARD C. REBATHOMAS W. SHEEHY, RICHARD C. REBAAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-4-807 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptInfection with Plasmodium falciparum may result in such potentially lethal complications as acute renal failure, blackwater fever, cerebral malaria, and pulmonary involvement. These complications developed in 1.1% of 3,300 cases in Vietnam (Table 1) and in them resulted in a total fatality rate of approximately 0.3%. Two factors correlated well with their development. One was an overwhelming infection; any patient with an intense parasitemia (400,000 parasites/mm3) was in danger of developing a major complication. The other was delay in treatment due either to misdiagnosis, to lack of a positive malaria smear, or to patients' failure to seek medical help.Diagnosis...References1. BROOKSMALLOYBARTELLONITIGERTTSHEEHYBARRY MHJPPJWDTWKG: The pathophysiology of acute falciparum malaria. I. Correlation of clinical and biochemical abnormalities. Amer. J. Med. In press. Google Scholar2. DENNISEICHELBERGERVONDOENHOFFCONRAD LHJWHEME: A coagulation defect and its treatment with heparin in Plasmodium knowlesi malaria in rhesus monkeys. Milit. Med. 131 (suppl.): 1107, 1965. Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: THOMAS W. SHEEHY; RICHARD C. 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