Portal de Periódicos da CAPES

Predictive docking of protein—protein and protein—DNA complexes

1998; Elsevier BV; Volume: 8; Issue: 2 Linguagem: Inglês

10.1016/s0959-440x(98)80047-x

1879-033X

Michael J.E. Sternberg, Henry A. Gabb, Richard M. Jackson,

Enzyme Structure and Function

Recent developments in algorithms to predict the docking of two proteins have considered both the initial rigid-body global search and subsequent screening and refinement. The results of two blind trials of protein docking are encouraging — for complexes that are not too large and do not undergo sizeable conformational change upon association, the algorithms are now able to suggest reasonably accurate models.