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Evaluation of polymethylmethacrylate as ocular implant in rabbits subjected to evisceration

2012; UNIVERSIDADE FEDERAL DE VIÇOSA; Volume: 59; Issue: 4 Linguagem: Inglês

10.1590/s0034-737x2012000400004

2177-3491

Arianne Pontes Oriá, Francisco de Assis Dórea Neto, Luís Alberto dos Santos, Evandro de Toledo Piza, Adriana Torrecilhas Jorge Brunelli, Celina Tie Nishimori, Ana Letícia Groszewicz de Souza, Deusdete Conceição Gomes, José Luiz Laus,

Intraocular Surgery and Lenses

Spheres of different types of material are used for the replacement of lost volume after removal of the eye bulb or its content to prevent contraction of the orbital cavity. The aim of this study was to evaluate the scope of polymethylmethacrylate (PMMA) used as intraocular implant in eviscerated rabbit eye. Twelve New Zealand rabbits underwent unilateral evisceration of the left eye, with subsequent implantation of PMMA sphere 12 mm in diameter. Clinical evaluation was performed daily during the first 15 days after surgery and every 15 days until the end of the study period (180 days). For the histopathological analysis, three animals per trial underwent enucleation at 15, 45, 90 and 180 days after evisceration. There was no wound dehiscence, signs of infection or implant extrusion in any animal throughout the study period. Histological examination revealed the formation of fibrovascular tissue around the implants. The PMMA behaved as inert and non-integrable.