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BIBTEX RIS

An ent-Kaurane-Type Diterpene in Croton antisyphiliticus Mart.

2012; Multidisciplinary Digital Publishing Institute; Volume: 17; Issue: 8 Linguagem: Inglês

10.3390/molecules17088851

ISSN

1433-1373

Autores

Sarazete Izidia Vaz Pereira, Sílvia Helena Taleb Contini, Juliana da Silva Coppede, Paulo Sérgio Pereira, Bianca Waléria Bertoni, Suzelei de Castro França, Ana Maria Soares Pereira,

Tópico(s)

Insect Pest Control Strategies

Resumo

Croton antisyphiliticus is a medicinal plant widely used in the treatment of microbial infections, especially those affecting the genital tract. Crude extract, fractions and pure compound isolated from roots of this species were investigated to validate their antimicrobial activity against Escherichia coli and Staphylococcus aureus. The compound ent-kaur-16-en-18-oic acid was isolated as a major component (0.7% of crude extract), and its MIC value determined against S. aureus (ATCC 6538) was 250 μg/mL. This is the first phytochemical work on the species monitored with antimicrobial assay.

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