Synthesis of novel aza analogues of 2-substituted-2,3-dihydro-1,4-benzodioxins as potential new scaffolds for drug discovery
2003; Elsevier BV; Volume: 44; Issue: 11 Linguagem: Inglês
10.1016/s0040-4039(03)00281-8
ISSN1873-3581
AutoresEncarna Matesanz, Jesús Alcázar, José Ignacio Andrés, José M. Bartolomé, Marcel De Bruyn, Javier Fernández, Kristof Van Emelen,
Tópico(s)Synthesis of heterocyclic compounds
ResumoNew synthesis approaches that have led to a series of novel aza analogues of the 2-substituted-2,3-dihydro-1,4-benzodioxin core, bearing versatile bromomethyl group on the non aromatic oxygenated ring, are described. According to their structures these novel scaffolds can be useful intermediates for the preparation of potential new therapeutic agents.
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