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Poisoning Caused by the Combined Ingestion of Nifedipine and Metoprolol

1993; Marcel Dekker; Volume: 31; Issue: 4 Linguagem: Inglês

10.3109/15563659309025766

1097-9875

Hiroshi Takahashi, Noriyoshi Ohashi, Kyoko Motokawa, Shigehito Sato, Hiroshi Naito,

Epilepsy research and treatment

Poisonings due to ingestion of a calcium channel or beta-adrenergic blocker have been the subject of several previous reports, but reports of poisoning due to combined ingestion of these drugs are infrequent. This is a report of suicidal ingestion of nifedipine 600 mg, metoprolol 200 mg, and etizolam 20 mg. Intravenous dopamine, norepinephrine, and calcium chloride had little effect but the administration of methylprednisolone and glucagon were associated with an increase in systolic blood pressure above 100 mm Hg.