Cytoprotective activity of pectic polysaccharides from the root of Panax ginseng
1991; Elsevier BV; Volume: 31; Issue: 1 Linguagem: Inglês
10.1016/0378-8741(91)90148-7
ISSN1872-7573
AutoresXiao-Bo Sun, Tsukasa Matsumoto, Hiroaki Kiyohara, Masumi Hirano, Haruki Yamada,
Tópico(s)Polysaccharides Composition and Applications
ResumoAn acidic polysaccharide fraction, GRA-4, of the root extract of Panax ginseng, when administered from 50 to 200 mg/kg orally, inhibited gastric lesions induced by HCl-ethanol or absolute ethanol, in a dose-dependent manner. The cytoprotective activity of GRA-4 decreased after its treatment with periodate but not after protein digestion, indicating that the carbohydrate moiety of this acidic polysaccharide contributes to this activity.
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