
Análise quantitativa de mastócitos e de granulócitos eosinófilos no miocárdio de ratos wistar cronicamente infectados pelo Trypanosoma cruzi. Contribuição ao conhecimento da fibrose miocárdia
1992; Brazilian Society of Tropical Medicine; Volume: 25; Issue: 1 Linguagem: Inglês
10.1590/s0037-86821992000100007
ISSN1678-9849
AutoresMaria da Conceição Nascimento Pinheiro, Paulo Sérgio Siebra Beraldo, Luiz Fernando Junqueira, Edison Reis Lopes, E Chapadeiro,
Tópico(s)Trypanosoma species research and implications
ResumoWe did mast cell and eosinophil granulocyte counts in the myocardium of forty chronic chagasic Wistar albino rats. We used 10 controls rats and 30 animals with late-stage (8th month) infection of São Felipe, Y and Colombian Trypanosoma cruzi strains, with variable degree of chronic myocarditis. We found chronic fibrosing myocarditis (fibrosis) in 40% of the infected animals. It was detected increased mast cell count in the chagasic rats associated with infection and not related with myocardial fibrosis. There was no increase in the eosinophil counts.
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