Artigo Produção Nacional Revisado por pares

Attempts to produce megasyndrome in mice using stocks of Trypanosoma cruzi associated with megaoesophagus in man

1979; Oxford University Press; Volume: 73; Issue: 6 Linguagem: Inglês

10.1016/0035-9203(79)90013-0

ISSN

1878-3503

Autores

Philip D. Marsden, Nelson J. Alvarenga, V. A. Soares, M.P. Gama,

Tópico(s)

Eosinophilic Esophagitis

Resumo

Two stocks of Trypanosoma cruzi isolated from patients with advanced megaoesophagus produced megastomach in chronically infected mice. The mice showed evidence of stomach dilatation and a delay in intestinal transit time. These findings are discussed in the light of the hypothesis that regional variations in T. cruzi determines mega formation in man.

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