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Development of the Terumo Capiox Centrifugal Pump and Its Clinical Application to Open Heart Surgery: A Comparative Study with the Roller Pump

1993; Wiley; Volume: 17; Issue: 5 Linguagem: Inglês

10.1111/j.1525-1594.1993.tb00588.x

1525-1594

Hiroshi Nishida, Fumiko Yamaki, Hayao Nakatani, Masahiro Endo, Hitoshi Koyanagi, Hiroaki Oshiyama, Kunio Horiuchi, Toshihiko Kijima, Chisato Nojiri, Hiromichi Fukasawa, Tetsuzo Akutsu,

Cardiac Valve Diseases and Treatments

Abstract: We have developed the Terumo Capiox centrifugal pump (CXP), which consists of a rotor having a unique straight‐path design to reduce pump rotational speed without decreasing hydraulic efficiency. The CXP was tested in vitro for blood trauma with a specially designed test circuit using fresh bovine blood. The Biopump (BP) (Medtronic, Minneapolis, MN, U.S.A.) and the roller pump (RP) were used as controls. The CXP demonstrated the smallest elevation of free plasma hemoglobin compared with the BP and the RP. The CXP was then applied to cardiopulmonary bypass (CPB) in 10 patients (CXP group) who underwent elective coronary artery by‐pass grafting (CABG), and the results were compared with those for a comparable roller pump group (RP group). Free plasma hemoglobin level, platelet count, and serum β ‐thromboglobulin ( β ‐TG) level were measured during CPB. There were no CXP‐related complications nor hemodynamic abnormalities during CPB. The CXP group demonstrated less hemolysis and less platelet depletion than the RP group. Furthermore, the serum β ‐TG level was significantly lower in the CXP group than in the RP group. The CXP showed excellent hemodynamic performance with less blood trauma both in vitro and in clinical application to open heart surgery. Thus, the CXP has significant potential to be safely applied to CPB for open heart surgery and circulatory support.