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Metabolic Hyperpolarization of Liver by Ethanol: The Importance of Mg 2+ and H + in Determining Impermeant Intracellular Anionic Charge and Energy of Metabolic Reactions

1994; Wiley; Volume: 18; Issue: 5 Linguagem: Inglês

10.1111/j.1530-0277.1994.tb00081.x

1530-0277

Richard L. Veech, Denise Gates, Calvin Crutchfield, William L. Gitomer, Yoshihiro Kashiwaya, Michael King, Robert Wondergern,

Renal function and acid-base balance

Alcoholism: Clinical and Experimental ResearchVolume 18, Issue 5 p. 1040-1056 Metabolic Hyperpolarization of Liver by Ethanol: The Importance of Mg2+ and H+ in Determining Impermeant Intracellular Anionic Charge and Energy of Metabolic Reactions Richard L. Veech, Corresponding Author Richard L. Veech Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Reprint requests: Richard L. Veech, Ph.D., Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, 12501 Washington Avenue, Rockville MD, 20852-1823.Search for more papers by this authorDenise N. Gates, Denise N. Gates Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorCalvin Crutchfield, Calvin Crutchfield Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorWilliam L. Gitomer, William L. Gitomer Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorYoshihiro Kashiwaya, Yoshihiro Kashiwaya Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorM. Todd King, M. Todd King Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorRobert Wondergern, Robert Wondergern Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this author Richard L. Veech, Corresponding Author Richard L. Veech Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Reprint requests: Richard L. Veech, Ph.D., Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, 12501 Washington Avenue, Rockville MD, 20852-1823.Search for more papers by this authorDenise N. Gates, Denise N. Gates Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorCalvin Crutchfield, Calvin Crutchfield Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorWilliam L. Gitomer, William L. Gitomer Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorYoshihiro Kashiwaya, Yoshihiro Kashiwaya Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorM. Todd King, M. Todd King Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this authorRobert Wondergern, Robert Wondergern Laboratory of Metabolism and Molecular Biology, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland; and the Department of Physiology, Quillen College of Medicine, East Tennessee State University, Johnson City, Tennessee.Search for more papers by this author First published: October 1994 https://doi.org/10.1111/j.1530-0277.1994.tb00081.xCitations: 17 This study was supported in part by the National Institute on Alcohol Abuse and Alcoholism, Grant AA-08867. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Jones JE, Shane SR, Jacobs WH, Flink EB: Magnesium balance studies in chronic alcoholism. Ann NY Acad Sci pp 934–946, 1968. 2 Knochel JP: Cardiovascular effects of alcohol. Ann Intern Med 98: 849–854, 1983. 3 Altura BM, Altura BT: Peripheral and cerebrovascular actions of ethanol, acetaldehyde and acetate: relationship to divalent cations. Alcohol Clin Exp Res 11: 99–111, 1987. 4 Friedman HS: Alcohol, arrhythmia, and sudden death. 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