Voltar
Revisão Acesso aberto Revisado por pares
BIBTEX RIS

Orchestration of Metabolism by Macrophages

2012; Cell Press; Volume: 15; Issue: 4 Linguagem: Inglês

10.1016/j.cmet.2011.11.013

ISSN

1932-7420

Autores

Subhra K. Biswas, Alberto Mantovani,

Tópico(s)

Neuroinflammation and Neurodegeneration Mechanisms

Resumo

Metabolic adaptation is a key component of macrophage plasticity and polarization, instrumental to their function in homeostasis, immunity, and inflammation. Macrophage products also impact metabolism, as illustrated by obesity-associated pathologies. Defining the mechanisms regulating macrophage metabolic activity and orchestration of metabolism by macrophages is crucial to pathology and therapeutic intervention.

Referência(s)