Artigo Revisado por pares

Distribution and Properties of Human Alcohol Dehydrogenase Isoenzymes

1987; Wiley; Volume: 492; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1987.tb48648.x

ISSN

1749-6632

Autores

Ting‐Kai Li, William Bosron,

Tópico(s)

Liver Disease Diagnosis and Treatment

Resumo

Annals of the New York Academy of SciencesVolume 492, Issue 1 p. 1-10 Distribution and Properties of Human Alcohol Dehydrogenase Isoenzymes TING-KAI LI, TING-KAI LI Indiana University School of Medicine, and Veterans Administration Medical Center Indianapolis, Indiana 46223Search for more papers by this authorWILLIAM F. BOSRON, WILLIAM F. BOSRON Indiana University School of Medicine, and Veterans Administration Medical Center Indianapolis, Indiana 46223Search for more papers by this author TING-KAI LI, TING-KAI LI Indiana University School of Medicine, and Veterans Administration Medical Center Indianapolis, Indiana 46223Search for more papers by this authorWILLIAM F. BOSRON, WILLIAM F. BOSRON Indiana University School of Medicine, and Veterans Administration Medical Center Indianapolis, Indiana 46223Search for more papers by this author First published: April 1987 https://doi.org/10.1111/j.1749-6632.1987.tb48648.xCitations: 16AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Blair, A. H. & B. L. Vallee. 1966. Some catalytic properties of human liver alcohol dehydrogenase. Biochemistry 5: 2026–2034. 2 Bosron, W. F. & T. -K. Li. 1981. Genetic determinants of alcohol and aldehyde dehydrogenases and alcohol metabolism. Seminars in Liver Dis. 1: 179–188. 3 Smith, M., D. A. Hopkinson & H. Harris. 1971. Developmental changes and polymorphism in human alcohol dehydrogenase. Ann. Hum. Genet. Lond. 34: 251–271. 4 Smith, M., D. A. Hopkinson & H. Harris. 1972. Alcohol dehydrogenase isozymes in adult human stomach and liver: evidence for activity of the ADH3 locus. Ann. Hum. Genet. Lond. 35: 243–253. 5 Li, T.-K. & L. J. Magnes. 1975. Identification of a distinctive molecular form of alcohol dehydrogenase in human livers with high activity. Biochem. Biophys. Res. Commun. 63: 202–208. 6 Bosron, W. F., T. -K. Li & B. L. Vallee. 1980. New molecular forms of human liver alcohol dehydrogenase: isolation and characterization of ADHIndianapolis Proc. Natl. Acad. Sci. 77: 5784–5788. 7 Parés, X. & B. L. Vallee. 1981. New human liver alcohol dehydrogenase forms with unique kinetic characteristics. Biochem. Biophys. Res. Commun. 98: 122–130. 8 Lange, L. G. & B. L. Vallee. 1976. Double-ternary complex affinity chromatography: preparation of alcohol dehydrogenases. Biochemistry 15: 4681–4686. 9 Bosron, W. F., L. J. Magnes & T. -K. Li. 1983. Kinetic and electrophoretic properties of native and recombined isoenzymes of human liver alcohol dehydrogenase. Biochemistry 22: 1852–1857. 10 Harada, S., D. P. Agarwal & H. W. Goedde. 1978. Human liver alcohol dehydrogenase isoenzyme variations. Improved separation methods using prolonged high voltage starch gel electrophoresis and isoelectric focusing. Hum. Genet. 40: 215–220. 11 Yin, S. -J., W. F. Bosron, L. J. Magnes & T. -K. Li. 1984. Human liver alcohol dehydrogenase: Purification and kinetic characterization of the β2β2, β2β1, αβ2, and β2, 1, "Oriental" isoenzymes. Biochemistry 23: 5847–5853. 12 Smith, M., D. A. Hopkinson & H. Harris. 1973. Studies on the subunit structure and molecular size of human alcohol dehydrogenase isoenzymes determined by the different loci, ADH1, ADH2 and ADH3, Ann. Hum. Genet. 37: 49–67. 13 Bosron, W. F., L. J. Magnes & T. -K. Li. 1983. Human liver alcohol dehydrogenase: ADHIndianapolis results from genetic polymorphism at the ADH2 gene locus. Biochem. Genet. 21: 735–744. 14 Adinolfi, A., M. Adinolfi, D. A. Hopkinson & H. Harris. 1978. Immunological properties of the human alcohol dehydrogenase isozymes. J. Immunogenet. 5: 283–296. 15 Strydom, D. J. & B. L. Vallee. 1982. Characterization of human alcohol dehydrogenase isoenzymes by high-performance liquid chromatographic peptide mapping. Anal. Biochem. 123: 422–429. 16 Hempel, J., R. Bühler, R. Kaiser, B. Holmquist, C. De Zalenski, J. P. von Wartburg, B. Vallee & H. Jornvall. 1984. Human liver alcohol dehydrogenase. 1. The primary structure of the β1β1 isoenzyme. Eur. J. Biochem. 145: 437–445. 17 Bühler, R., J. Hempel, R. Kaiser, C. De Zalenski, J. -P. von Wartburg & H. Jornvall. 1984. Human liver alcohol dehydrogenase. 2. The primary structure of the 1 protein chain. Eur. J. Biochem. 145: 447–453. 18 Hempel, J., B. Holmquist, L. Fleetwood, R. Kaiser, J. Barros-Soderling, R. Bühler, B. L. Vallee & H. Jornvall. 1985. Structural relationships among class I isozymes of human liver alcohol dehydrogenase. Biochemistry 24: 5303–5307. 19 Wagner, F. W., A. R. Burger & B. L. Vallee. 1983. Kinetic properties of human liver alcohol dehydrogenase: oxidation of alcohols by class I isoenzymes. Biochemistry 22: 1857–1863. 20 Vallee, B. L. & T. J. Bazzone. 1983. Isozymes of human liver alcohol dehydrogenase. Isozymes: Current Topics in Biological and Medical Research, Cellular Localization, Metabolism, and Physiology 8: 219–244. 21 Adinolfi, A., M. Adinolfi & D. A. Hopkinson. 1984. Immunological and biochemical characterization of the human alcohol dehydrogenase chi-ADH isozyme. Ann. Hum. Genet. 48: 1–10. 22 Beisswenger, T. B., B. Holmquist & B. L. Vallee. 1985. -ADH is the sole alcohol dehydrogenase isozyme of mammalian brains: implications and inferences. Proc. Natl. Acad. Sci. 82: 8368–8373. 23 Teng, Y. -S., S. Jehan & L. E. Lei-Injo. 1979. Human alcohol dehydrogenase ADH2 and ADH3 polymorphisms in ethnic Chinese and Indians of West Malaysia. Hum. Genet. 53: 87–90. 24 Yin, S. -J., W. F. Bosron, T. -K. Li, K. Ohnishi, K. Okuda, H. Ishii & M. Tsuchiya. 1984. Polymorphism of human liver alcohol dehydrogenase: identification of ADH2 2–1 and ADH2 2-2 phenotypes in the Japanese by isoelectric focusing. Biochem. Genet. 22: 169–180. 25 Azevedo, E. S., C. B. O. da Silva & J. Tavares-Neto. 1975. Human alcohol dehydrogenase ADH1, ADH2 and ADH3 loci in a mixed population of Bahia, Brazil. Ann. Hum. Genet. 39: 321–327. 26 Harada, S., S. Misawa, D. P. Agarwal & H. W. Goedde. 1980. Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication. Am. J. Hum. Genet. 32: 8–15. 27 von Wartburg, J. -P. & P. M. Schurch. 1968. Atypical human liver alcohol dehydrogenase. Ann. N. Y. Acad. Sci. 151: 936–946. 28 Jörnvall, H., J. Hempel, B. L. Vallee, W. F. Bosron & T. -K. Li. 1984. Human liver alcohol dehydrogenase: amino acid substitution in the β2β2 Oriental isozyme explains functional properties, establishes an active site structure, and parallels mutational exchanges in the yeast enzyme. Proc. Natl. Acad. Sci. 81: 3024–3028. 29 Ikuta, T., T. Fujiyoshi, K. Kurachi & A. Yoshida. 1985. Molecular cloning of full-length cDNA for human alcohol dehydrogenase. Proc. Natl. Acad. Sci. 82: 2703–2707. 30 Ikuta, T., S. Szeto & A. Yoshida. 1986. Three human alcohol dehydrogenase subunits: cDNA structure and molecular and evolutionary divergence. Proc. Natl. Acad. Sci. 83: 634–638. 31 Deuster, G., M. Smith, V. Blanchione & G. W. Hatfield. 1986. Molecular analysis of the human class I alcohol dehydrogenase gene family and nucleotide sequence of the gene encoding the β subunit. J. Biol. Chem. 162: 2027–2033. 32 Smith, M. 1986. Genetics of human alcohol and aldehyde dehydrogenase. Adv. Hum. Genet. 15: 249–290. 33 Bosron, W. F., T.-K. Li, W. P. Dafeldecker & B. L. Vallee. 1979. Human liver -alcohol dehydrogenase: kinetic and molecular properties. Biochemistry 18: 1101–1105. 34 Li, T. -K., W. F. Bosron, W. P. Dafeldecker, L. G. Lange & B. L. Vallee. 1977. Isolation of α-alcohol dehydrogenase of human liver: Is it a determinant of alcoholism Proc. Natl. Acad. Sci. 74: 4378–4381. 35 Ditlow, C. C., B. Holmquist, M. M. Morelock & B. L. Vallee. 1984. Physical and enzymatic properties of a class II alcohol dehydrogenase isozyme of human liver: -ADH. Biochemistry 23: 6363–6368. 36 Keung, W. M., C. C. Ditlow & B. L. Vallee. 1985. Identification of human alcohol dehydrogenase isozymes by disc polyacrylamide gel electrophoresisin 7 M urea. Anal. Biochem. 151: 92–96. 37 Dafeldecker, W. P. & B. L. Vallee. 1986. Organ-specific human alcohol dehydrogenase: isolation and characterization of isozymes from testis. Biochem. Biophys. Res. Commun. 134: 1056–1063. 38 Burnell, J. C., W. F. Bosron & T. -K. Li. 1986. Kinetic characterizationof human liver β3β3 (βIndianapolis)alcohol dehydrogenase. Fed. Proc. 45: 1504. 39 Eklund, H., J. -P. Samama & T. A. Jones. 1984. Crystallographic investigations of nicotinamide adenine dinucleotide binding to horse liver alcohol dehydrogenase. Biochemistry 23: 5982–5996. 40 Li, T. -K. 1983. The absorption, distribution and metabolism of ethanol and its effects on nutrition and hepatic function. In Medical and Social Aspects of Alcohol Abuse. B. Tabakoff, P. B. Sutker, and C. L. Randall, Eds. 47–77. Plenum. New York , NY . 41 Kopun, M. & P. Propping. 1977. The kinetics of ethanol absorption and elimination in twins and supplementary repetitive experiments in singleton subjects. Eur. J. Clin. Pharmacol. 11: 337–344. 42 Martin, N. G., J. Perl, J. G. Oakeshott, J. B. Gibson, G. A. Starmer & A. V. Wilks. 1985. A twin study of ethanol metabolism. Behav. Genet. 15: 93–109. Citing Literature Volume492, Issue1Alcohol and the CellApril 1987Pages 1-10 ReferencesRelatedInformation

Referência(s)