Single Walled Carbon Nanotubes/polypyrrole–GOx composite films to modify gold microelectrodes for glucose biosensors: Study of the extended linearity
2012; Elsevier BV; Volume: 43; Linguagem: Inglês
10.1016/j.bios.2012.11.019
ISSN1873-4235
AutoresFederica Valentini, L. Galache Fernàndez, Emanuela Tamburri, Giuseppe Palleschi,
Tópico(s)Conducting polymers and applications
ResumoA glucose biosensor was assembled using gold microelectrodes (diameter of 250 μm) coated by Single-Walled Carbon Nanotubes (SWCNTs), via the Electrophoresis Deposition Process (EPD). This nanostructured platform was successfully used to deposit the poly(pyrrole)/glucose oxidase film (PPy/GOx). The most important result of this biosensors was the wide linear range of concentration, ranging from 4 to100 mM (covering the hypo- and hyper-glycemia range, useful in diabetes). This extended linearity offered the possibility to measure glucose from 0.560 to 12.0 mM, with a detection limit of 50 μM (useful for hypo-glycemia disease).
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