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BIBTEX RIS

Design and Synthesis of Biotin Chain-Terminated Glycopolymers for Surface Glycoengineering

2002; American Chemical Society; Volume: 124; Issue: 25 Linguagem: Inglês

10.1021/ja025788v

ISSN

1943-2984

Autores

Xue‐Long Sun, Keith M. Faucher, Michelle Houston, Daniel Grande, Elliot L. Chaikof,

Tópico(s)

Advanced Biosensing Techniques and Applications

Resumo

Biotin chain-terminated glycopolymers were generated by cyanoxyl-mediated free-radical polymerization using a biotin-derivatized arylamine initiator with high conversion (75%) and low polydispersity (1.30). Streptavidin-biotinylated glycopolymer binding was verified by SDS-PAGE gel shift assay and patterned glycocalyx-mimetic surfaces successfully fabricated.

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