Produção Nacional
Revisado por pares
Neuronal counting and parasympathetic dysfunction in the hearts of chronically Trypanosoma cruzi - infected rats
1991; UNIVERSIDADE DE SÃO PAULO; Volume: 33; Issue: 5 Linguagem: Inglês
10.1590/s0036-46651991000500001
ISSN1678-9946
AutoresE Chapadeiro, R.F.C. Florêncio, Paula Afonso, Paulo Sérgio Siebra Beraldo, Paulo César de Jesus, Luiz Fernando Junqueira,
Tópico(s)Trypanosoma species research and implications
ResumoTen male Wistar rats, chronically infected with Colombian, São Felipe (12SF) and Y strains of Trypanosoma cruzi and ten non-infected control animals were submitted to the bradycardia responsiveness test, an assessment of heart parasympathetic function, after phenylephrine injection. Six chagasic animals showed heart parasympathetic dysfuntion characterized by reduction in the index of bradycardia baroreflex responsiveness, as compared with the control group. Microscopic examination of the atrial heart ganglia of chagasic rats showed ganglionitis, but no statiscally significant reduction in the number of neurons.
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