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PEPTIC STRICTURES OF THE ESOPHAGUS

1999; Elsevier BV; Volume: 28; Issue: 4 Linguagem: Inglês

10.1016/s0889-8553(05)70095-9

1558-1942

Joel E. Richter,

Eosinophilic Esophagitis

The clinical spectrum of gastroesophageal reflux disease (GERD) is diverse. Most patients follow a benign course characterized by intermittent heartburn and acid regurgitation. Nearly 40% develop esophagitis, however, which may be severe in half of these cases. One of the most frequent sequelae of long-standing severe esophagitis is the formation of a peptic esophageal stricture. The morbidity faced by patients with peptic strictures is significant and derives from their potential to have a chronic relapsing course, increased risk of food impaction, propensity for pulmonary aspiration, frequent coexistent Barrett's esophagus, and the need for esophageal dilation occasionally complicated by perforation. This article reviews the pathophysiology, predisposing factors, clinical presentation, diagnosis, and treatment of peptic strictures.