A Six‐Month Clinical Evaluation of Decalcified Freeze‐Dried Bone Allografts in Periodontal Osseous Defects
1982; Wiley; Volume: 53; Issue: 12 Linguagem: Inglês
10.1902/jop.1982.53.12.726
ISSN1943-3670
AutoresGeorge Quintero, James T. Mellonig, Vernon M. Gambill, George B. Pelleu,
Tópico(s)Bone Tissue Engineering Materials
ResumoT he osteogenic potential of decalcified freeze‐dried bone allografts in the treatment of human periodontal osseous defects was evaluated over a 6‐month period. Cortical bone, obtained under sterile conditions from a human donor within 24 hours after death, was decalcified, freeze‐dried and ground to a particle size of 250 to 500 μ m. Twenty‐seven osseous defects with one‐, two‐ and wide three‐wall morphology were treated. Clinical measurements were made with a stent and a calibrated periodontal probe before surgery, at the time of surgery, and at re‐entry. The combined mean osseous regeneration for all defects was 2.4 mm. This represented a 65% mean bone‐fill of the original defect. The findings demonstrate that decalcified freeze‐dried bone allograft has potential as an osseous grafting material in periodontal therapy.
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