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Large Fetal Sacrococcygeal Teratomas: Could Early Delivery Improve Outcome?

2008; Karger Publishers; Volume: 24; Issue: 1 Linguagem: Inglês

10.1159/000132408

1421-9964

Cynthia J. Holcroft, Karin J. Blakemore, Edith D. Gurewitsch, Rita W. Driggers, Frances J. Northington, Anne Fischer,

Congenital Diaphragmatic Hernia Studies

<i>Objective:</i> To determine if gestational age (GA) at delivery or tumor size impacts outcome in neonates with very large sacrococcygeal teratomas (SCTs). <i>Methods:</i> Retrospective chart review from 1990 to 2006 of live-born infants with very large SCTs, defined as diameters exceeding 10 cm. Data analyzed using the independent t test and Fisher’s exact test, with p values <0.05 considered significant. <i>Results:</i> Nine infants with very large SCTs were identified. Six of the 9 infants survived, 4 of whom had evidence of early hydrops. Mean GA of survivors was 32.2 ± 3.7 versus 31.7 ± 0.6 weeks in nonsurvivors (p = 0.85). Infants with the largest SCTs did not survive. <i>Conclusion:</i> Risks of preterm delivery must be weighed against complications from further enlargement of very large SCTs and against the risks of in utero intervention.