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Epidemiology of congenital pigmented naevi: I. Incidence rates and relative frequencies

1981; Oxford University Press; Volume: 104; Issue: 3 Linguagem: Inglês

10.1111/j.1365-2133.1981.tb00954.x

1365-2133

Eduardo E. Castilla, Maria da Graça Dutra, IEDA M. ORIOLI-PARREIRAS,

Genetic and rare skin diseases.

British Journal of DermatologyVolume 104, Issue 3 p. 307-315 Epidemiology of congenital pigmented naevi: I. Incidence rates and relative frequencies EDUARDO E. CASTILLA, EDUARDO E. CASTILLA Departamento de Genetica, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Ilha do Fundão, 20.000, Rio, RJ, BrazilSearch for more papers by this authorMARIA DA GRAÇA DUTRA, MARIA DA GRAÇA DUTRA Departamento de Genetica, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Ilha do Fundão, 20.000, Rio, RJ, BrazilSearch for more papers by this authorIÊDA M. ORIOLI-PARREIRAS, IÊDA M. ORIOLI-PARREIRAS Departamento de Genetica, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Ilha do Fundão, 20.000, Rio, RJ, BrazilSearch for more papers by this author EDUARDO E. CASTILLA, EDUARDO E. CASTILLA Departamento de Genetica, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Ilha do Fundão, 20.000, Rio, RJ, BrazilSearch for more papers by this authorMARIA DA GRAÇA DUTRA, MARIA DA GRAÇA DUTRA Departamento de Genetica, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Ilha do Fundão, 20.000, Rio, RJ, BrazilSearch for more papers by this authorIÊDA M. ORIOLI-PARREIRAS, IÊDA M. ORIOLI-PARREIRAS Departamento de Genetica, Instituto de Biologia, Universidade Federal do Rio de Janeiro, Ilha do Fundão, 20.000, Rio, RJ, BrazilSearch for more papers by this author First published: March 1981 https://doi.org/10.1111/j.1365-2133.1981.tb00954.xCitations: 275AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat SUMMARY Pigmented naevi (PN) were clinically diagnosed in 1083 newborn infants from a series of 531,831 consecutive livebirths examined in fifty-nine hospitals in South America. Isolated PN (IPN) were seen in 989 (0.2%) non-malformed infants, while PN associated with other congenital anomalies (APN) were observed in ninety-four (1.0%) malformed babies. Incidence rates calculated from the fifty-nine hospitals were very variable due to under-reporting, which might have been as high as 80%. The PN were classified by their location, number, size, texture, and colour. Observed locations were compared with random expected distributions based on the surface proportions of the newborn. IPN were preferentially found on the chest and abdomen, with a low concentration on the head and upper limbs. No examples were observed on soles or palms. IPN were single in 90% of cases. Size was small (1–9 mm) in 29%, medium (10–;40 mm) in 63%, and large (over 40 mm) in 8% of cases. Abnormal texture, (rugose, raised, and/or hairy) was found in 7–11% of IPN. Colour was brown in 68%, black in 21%, and of other colours in 11%. The large IPN tended to be multiple in number and abnormal in texture. Small IPN tended to be black. IPN on the chest and abdomen were more frequently small, non-black, and of normal texture; those found on the back tended to be black and abnormal in texture; black IPN were also frequent on the upper limbs; large IPN frequently affected the lower limbs. The APN did not differ from the IPN in their number, size, texture, or colour. APN were less common than expected on the back and upper limbs. An association was observed between the PN and the following four congenital anomalies: ear deformities, preauricular appendages, angiomas, and other skin anomalies. The differences in distribution of PN in the newborn infant and that in the adult that have been previously published suggest that most of the PN found in the adult are not congenital. Citing Literature Volume104, Issue3March 1981Pages 307-315 RelatedInformation