Autogenous cancellous-marrow bone grafts in irradiated dog mandibles

1977; Elsevier BV; Volume: 43; Issue: 3 Linguagem: Inglês

10.1016/0030-4220(77)90322-x

ISSN

1878-2175

Autores

Robert D. Marciani, Arthur A. Gonty, Joseph S. Giansanti, José Antônio Carvalho de Ávila,

Tópico(s)

Reconstructive Surgery and Microvascular Techniques

Resumo

A pilot study was conducted to investigate the osteogenic potential of autogenous cancellous-marrow grafts in irradiated tissue. Three young adult mongrel dogs with large mandibles were used in this preliminary experiment. Each dog mandible received 500 rads of cobalt irradiation twice a week for 5 weeks. Discontinuity defects were created in the mandible and reconstructed immediately with a cancellous-marrow graft. Bony union occurred in all the mandibles. The quantity of new bone formed in the surgical defect varied. The graft sites showed a histologic picture generally similar to the nonsurgical side.

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