Epoxidation of Olefinic Compounds with Combined Use of Molecular Oxygen and Propionaldehyde Diethyl Acetal Catalyzed by Cobalt(II) Complex. Efficient Method for the Preparation of Acid-sensitive Epoxides
1993; Oxford University Press; Volume: 22; Issue: 9 Linguagem: Inglês
10.1246/cl.1993.1579
ISSN1348-0715
AutoresKiyotaka Yorozu, Toshihiro Takai, Tohru Yamada, Teruaki Mukaiyama,
Tópico(s)Organic Chemistry Cycloaddition Reactions
ResumoAbstract Synthesis of acid-sensitive epoxides such as epoxide of bishomoallyl alcohol or chromene oxide was achieved by the epoxidation of corresponding olefins with combined use of molecular oxygen and propionaldehyde diethyl acetal catalyzed by cobalt(II) complex. Various silyl enol ethers and silyl ketene acetals, acid-sensitive compounds, were also smoothly monooxygenated into the corresponding α-hydroxy carbonyl compounds.
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