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Radial Glial Cells

2005; Cell Press; Volume: 46; Issue: 3 Linguagem: Inglês

10.1016/j.neuron.2005.04.012

1097-4199

Magdalena Götz, Yves‐Alain Barde,

MicroRNA in disease regulation

Radial glial cells have been identified as a major source of neurons during development. Here, we review the evidence for the distinct "glial" nature of radial glial cells and contrast these cells with their progenitors, the neuroepithelial cells. Recent results also suggest that not only during neurogenesis in vivo, but also during the differentiation of cultured embryonic stem cells toward neurons, progenitors with clear glial antigenic characteristics act as cellular intermediates.