Portal de Periódicos da CAPES

A route for the enantioselective total synthesis of antheridic acid, the antheridium-inducing factor from anemia phyllitidis

1991; Elsevier BV; Volume: 32; Issue: 38 Linguagem: Inglês

10.1016/s0040-4039(00)93418-x

1873-3581

E. J. Corey, Hideo Kigoshi,

Advanced Synthetic Organic Chemistry

An effective route for the total synthesis of antheridic acid (1) has been devised in which the initial chiral intermediate 7 is generated by enantioselective catalytic reduction and transformed in a stereocontrolled fashion into key intermediates 9, 10, 13, and 2.