Adult T-cell leukemia-lymphoma unusual features of two patients from a low-incidence area
1986; Wiley; Volume: 58; Issue: 3 Linguagem: Inglês
10.1002/1097-0142(19860801)58
ISSN1097-0142
AutoresJudith J. Temple, Melissa Brammer, W. Abe Andes, Steve Covington, S. R. S. Rangan,
Tópico(s)Animal Disease Management and Epidemiology
ResumoThe occurrence of adult T-cell leukemia-lymphoma in two New Orleans patients, one native-born, the other originally from Honduras, is reported. Both exhibited an unusual feature. One patient was diagnosed following an atypical episode of sinusitis and demonstrated lymphomatous infiltration of the nasopharynx. A second patient had a fulminant course complicated by severe diarrhea and was found to have both tumor involvement and cytomegalovirus inclusions in the colon. Both had high titers of antibodies to HTLV-I. A cell line with T-lymphocyte characteristics was established from the peripheral blood of the first patient. Such studies may help better establish the clinical course, detection, and epidemiologic features of this difficult disease.Cancer 58:694-698, 1986.
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