Portal de Periódicos da CAPES

Brain Regions Where Cholecystokinin Exerts Its Effect on Satietya

1994; Wiley; Volume: 713; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1994.tb44072.x

1749-6632

R. Schick, V. Schusdziarra, Tony L. Yaksh, Vay Liang W. Go,

Pharmacological Receptor Mechanisms and Effects

Annals of the New York Academy of SciencesVolume 713, Issue 1 p. 242-254 Brain Regions Where Cholecystokinin Exerts Its Effect on Satietya RAFAEL R. SCHICK, Corresponding Author RAFAEL R. SCHICK Department of Internal Medicine II Technical University of Munich D-81664 Munich, GermanyPriv. Doz. Dr. Rafael R. Schick, II. Medizinische Klinik und Poliklinik der Technischen Universität München, Klinikum rechts der Isar, D-81664 Munich, Germany.Search for more papers by this authorVOLKER SCHUSDZIARRA, VOLKER SCHUSDZIARRA Department of Internal Medicine II Technical University of Munich D-81664 Munich, GermanySearch for more papers by this authorTONY L. YAKSH, TONY L. YAKSH Department of Anesthesiology University of California San Diego, CaliforniaSearch for more papers by this authorVAY LIANG W. GO, VAY LIANG W. GO Department of Medicine University of California Los Angeles, CaliforniaSearch for more papers by this author RAFAEL R. SCHICK, Corresponding Author RAFAEL R. SCHICK Department of Internal Medicine II Technical University of Munich D-81664 Munich, GermanyPriv. Doz. Dr. Rafael R. Schick, II. Medizinische Klinik und Poliklinik der Technischen Universität München, Klinikum rechts der Isar, D-81664 Munich, Germany.Search for more papers by this authorVOLKER SCHUSDZIARRA, VOLKER SCHUSDZIARRA Department of Internal Medicine II Technical University of Munich D-81664 Munich, GermanySearch for more papers by this authorTONY L. YAKSH, TONY L. YAKSH Department of Anesthesiology University of California San Diego, CaliforniaSearch for more papers by this authorVAY LIANG W. GO, VAY LIANG W. GO Department of Medicine University of California Los Angeles, CaliforniaSearch for more papers by this author First published: March 1994 https://doi.org/10.1111/j.1749-6632.1994.tb44072.xCitations: 31 a These studies were supported by DFG (Schi 237/1–1, 237/2-1, 237/2-2: R.R.S.) and by NIH (AM-34988-P3 and AM-34988-CD: T.L.Y. and V.L.W.G.). AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Morley, J. E. 1987. Neuropeptide regulation of appetite and weight. Endocr. Rev. 8: 256–287. 2 Robinson, P. H., P. R. McHugh, T. H. Moran & J. D. Stephenson. 1988. Gastric control of food intake. J. Psychosom. Res. 32: 593–606. 3 Janowitz, H. D. & M. I. Grossman. 1949. Some factors affecting the food intake of normal dogs and dogs with esophagostomy and gastric fistula. Am. J. Physiol. 159: 143–148. 4 Geliebter, A., S. Westreich & D. Gage. 1988. Gastric distention by balloon and test-meal intake in obese and lean subjects. Am. J. Clin. Nutr. 48: 592–594. 5 Schick, R. R., V. Schusdziarra, B. Schröder & M. Classen. 1991. Effect of intraduodenal or intragastric nutrient infusion on food intake in man. Z. Gastroenterol. 29: 637–641. 6 Schick, R. R., B. Regensburger, B. Schröder & M. Classen. 1991. Role of gastric distention and nutrient content for satiety in humans. Gastroenterology 100: A546. 7 Grossman, S. P. 1975. Role of the hypothalamus in the regulation of food and water intake. Psychol. Rev. 82: 200–224. 8 Koopmans, H. S. 1983. A stomach hormone that inhibits food intake. J. Auton. Nerv. Syst. 9: 157–171. 9 Ewart, W. R. & D. L. Wingate. 1983. Central representation and opioid modulation of gastric mechanoreceptor activity in the rat. Am. J. Physiol. 244: G27–G32. 10 Hoffman, H. H. & H. Schnitzlein. 1969. The number of vagus nerves in man. Anat. Rec. 139: 429–435. 11 Ivy, A. C. & E. Oldberg. 1928. A hormone mechanism for gallbladder contraction and evacuation. Am. J. Physiol. 86: 599–613. 12 Gibbs, J., R. Young & G. P. Smith. 1973. Cholecystokinin decreases food intake in rats. J. Comp. Physiol. Psychol. 84: 488–495. 13 Pappas, T. N., R. L. Melendez, K. M. Strah & H. T. Debas. 1985. Cholecystokinin is not a peripheral satiety signal in the dog. Am. J. Physiol. 249: G733–G738. 14 Reidelberger, R. D. & T. E. Solomon. 1986. Comparative effects of CCK-8 on feeding, sham feeding and exocrine pancreatic secretion in rats. Am. J. Physiol. 251: R97–R105. 15 Schick, R. R., V. Schusdziarra, J. Mössner, J. Neuberger, B. Schröder, R. Segmüller, V. Maier & M. Classen. 1991. Effect of CCK on food intake in man: Physiological or pharmacological effect Z. Gastroenterol. 29: 53–58. 16 Smith, G. P., C. Jerome, J. Cushin, R. Eterno & K. J. Simansky. 1981. Abdominal vagotomy blocks the satiety effect of cholecystokinin in the rat. Science 213: 1036–1037. 17 Smith, P. G., E. Jerome & R. Norgren. 1985. Afferent axons in abdominal vagus mediate the satiety effect of cholecystokinin in rats. Am. J. Physiol. 249: R638–R641. 18 Crawley, J. N. & J. S. Schwaber. 1984. Abolition of the behavioral effects of cholecystokinin following bilateral radiofrequency lesions of the parvocellular subdivision of the nucleus tractus solitarius. Brain Res. 295: 289–299. 19 Crawley, J. N., J. Z. Kiss & E. Mezey. 1984. Bilateral midbrain transections block the behavioral effects of cholecystokinin on feeding and exploration in rats. Brain Res. 322: 316–321. 20 Crawley, J. N. & J. Z. Kiss. 1985. Paraventricular nucleus lesions abolish the inhibition of feeding induced by systemic cholecystokinin. Peptides 6: 927–935. 21 Hetherington, A. W. & S. W. Ranson. 1940. Hypothalamic lesions and adiposity in the rat. Anat. Rec. 78: 149–172. 22 Le Magnen, J. 1983. Body energy balance and food intake: A neuroendocrine regulatory mechanism. Physiol. Rev. 63: 314–386. 23 Anand, B. K. & J. R. Brobeck. 1951. Hypothalamic control of food intake in rats and cats. Yale J. Biol. Med. 24: 123–140. 24 Vanderhaeghen, J. J., F. Lotstra, J. Demey & C. Gilles. 1980. Immunohistochemical localization of cholecystokinin- and gastrin-like peptides in the brain and hypophysis of the rat. Proc. Natl. Acad. Sci. USA 77: 1190–1194. 25 Rehfeld, J. F., N. Gottermann, L.-I. Larsson, P. M. Emson & C. M. Lee. 1979. Gastrin and cholecystokinin in central and peripheral neurons. Fed. Proc. 38: 2325–2329. 26 Saito, A., H. Sankaran, I. D. Goldfine & J. A. Williams. 1980. Cholecystokinin receptors in the brain: Characterization and distribution. Science 208: 1155–1156. 27 Pinget, M., E. Straus & R. S. Yalow. 1979. Release of cholecystokinin peptides from a synaptosome-enriched fraction of rat cerebral cortex. Life Sci. 25: 339–342. 28 Wang, J.-Y., T. L. Yaksh & V. L. W. Go. 1983. In vivo studies on the basal and evoked release of cholecystokinin and vasoactive intestinal polypeptide from cat cerebral cortex and periventricular structures. Brain Res. 280: 105–117. 29 Dodd, J. & J. S. Kelly. 1979. Excitation of CA1 pyramidal neurons of the hippocampus by the tetra- and octapeptide C-terminal fragments of cholecystokinin. J. Physiol. (Lond.) 295: 61–62. 30 Straus, E., A. Malesci & R. S. Yalow. 1978. Characterization of a nontrypsin cholecystokinin converting enzyme in mammalian brain. Proc. Natl. Acad. Sci. USA 75: 5711–5714. 31 Della-Fera, M. A. & C. A. Baile. 1979. Cholecystokinin octapeptide—continuous picomole injections into the cerebral ventricles of sheep suppress feeding. Science 206: 471–473. 32 Parrott, R. F. & B. A. Baldwin. 1981. Operant feeding and drinking in pigs following intracerebroventricular injection of synthetic cholecystokinin octapeptide. Physiol. Behav. 26: 419–422. 33 Denbow, D. M. & R. D. Myers. 1982. Eating, drinking and temperature responses to intracerebroventricular cholecystokinin in the chick. Peptides 3: 739–743. 34 Miceli, M. O. & C. W. Malsbury. 1983. Feeding and drinking responses in the golden hamster following treatment with cholecystokinin and angiotensin II. Peptides 4: 103–106. 35 Sakatani, N., A. Inui, T. Inoue, M. Oya, H. Morioka & S. Baba. 1987. The role of cholecystokinin octapeptide in the central control of food intake in the dog. Peptides 8: 651–656. 36 Figlewicz, D. P., A. J. Sipolis, P. Green, D. Porte, Jr. & S. C. Woods. 1989. IVT CCK-8 is more effective than IV CCK-8 at decreasing meal size in the baboon. Brain Res. Bull. 22: 849–852. 37 Schick, R. R., T. L. Yaksh & V. L. W. Go. 1986. Intracerebroventricular injections of cholecystokinin octapeptide suppress feeding in rats: Pharmacological characterization of this action. Reg. Peptides 14: 277–291. 38 Stern, J. J., C. A. Cudillo & J. Kruper. 1976. Ventromedial hypothalamus and short-term feeding suppression by caerulein in male rats. J. Comp. Physiol. Psychol. 90: 484–490. 39 Maddison, S. 1977. Intraperitoneal and intracranial cholecystokinin depress operant responding for food. Physiol. Behav. 19: 819–824. 40 Schick, R. R., C. W. Stevens, T. L. Yaksh & V. L. W. Go. 1988. Chronic intraventricular administration of cholecystokinin octapeptide (CCK-8) suppresses feeding in rats. Brain Res. 448: 294–298. 41 Beinfeld, M. C. & M. Palkovits. 1981. Distribution of cholecystokinin (CCK) in the hypothalamus and limbic system of the rat. Neuropeptides 2: 123–129. 42 Micevych, P. E., V. L. W. Go & T. L. Yaksh. 1984. In vitro release of cholecystokinin from hypothalamus and frontal cortex of Sprague-Dawley, Zucker lean (Fa/-) and obese (fa/fa) rats. Peptides 5: 73–80. 43 McLaughlin, C. L., C. A. Baile, M. A. Della-Fera & T. G. Kasser. 1985. Meal-stimulated increased concentration of CCK in the hypothalamus of Zucker obese and lean rats. Physiol. Behav. 35: 215–220. 44 Pellegrino, L. J., A. S. Pellegrino & A. Cushman. 1979. A Stereotaxic Atlas of the Rat Brain. Plenum Press. New York , NY . 45 Schick, R. R., G. J. Harty, T. L. Yaksh & V. L. W. Go. 1990. Sites in the brain at which cholecystokinin octapeptide (CCK-8) acts to suppress feeding in rats: A mapping study. Neuropharmacology 29: 109–118. 46 Yaksh, T. L. & R. D. Myers. 1972. Neurohumoral substances released from hypothalamus of the monkey during hunger and satiety. Am. J. Physiol. 222: 503–515. 47 Yaksh, T. L. & H. I. Yamamura. 1974. Factors affecting performance of the push-pull cannula in brain. J. Appl. Physiol. 37: 428–434. 48 Schick, R. R., T. L. Yaksh & V. L. W. Go. 1991. Postprandial release of hypothalamic cholecystokinin (CCK). In Brain-Gut Interactions. Y. Taché & D. Wingate, Eds.: 267–278. CRC Press. Boca Raton , FL . 49 Schick, R. R., T. L. Yaksh & V. L. W. Go. 1986. An intragastric meal releases the putative satiety factor cholecystokinin from hypothalamic neurons in cats. Brain Res. 370: 349–353. 50 Schick, R. R., T. L. Yaksh, D. R. Roddy & V. L. W. Go. 1989. Release of hypothalamic cholecystokinin in cats: Effects of nutrient and volume loading. Am. J. Physiol. 256: R248–R254. 51 Schick, R. R., W. M. Reilly, D. R. Roddy, T. L. Yaksh & V. L. W. Go. 1987. Neuronal cholecystokinin-like immunoreactivity is postprandially released from primate hypothalamus. Brain Res. 418: 20–26. 52 Rehfeld, J. F. 1978. Immunochemical studies on cholecystokinin. II. Distribution and molecular heterogeneity in the central nervous system and small intestine of man and hog. J. Biol. Chem. 253: 4022–4030. 53 Walsh, J. H., C. B. Lamers & J. E. Valenzuela. 1982. Cholecystokinin octapeptide-like immunoreactivity in human plasma. Gastroenterology 82: 438–444. 54 Oldendorf, W. H. 1981. Blood-brain barrier permeability to peptides: Pitfalls in measurement. Peptides 2 (Suppl. 2): 109–111. 55 Moran, T. H., P. H. Robinson, M. S. Goldrich & P. R. McHugh. 1986. Two brain cholecystokinin receptors: Implications for behavioral actions. Brain Res. 362: 175–179. 56 Dourish, C. T. & D. R. Hill. 1987. Classification and function of CCK receptors. Trends Pharmacol. Sci. 8: 207–208. 57 Hill, D. R. & T. M. Shaw. 1988. In Cholecystokinin Antagonists. R. Y. Wang & R. Schoenfeld, Eds.: 133–148. Alan R. Liss. New York , NY . 58 Lotti, V. J. & R. S. L. Chang. 1989. A new potent and selective non-peptide gastrin antagonist and brain cholecystokinin receptor (CCK-B) ligand: L-365,260. Eur. J. Pharmacol. 162: 273–280. 59 Lotti, V. J., R. G. Pendleton, R. J. Gould, H. M. Hanson, R. S. L. Chang & B. V. Clineschmidt. 1987. In vivo pharmacology of L-364,718, a new potent nonpeptide peripheral cholecystokinin antagonist. J. Pharmacol. Exp. Ther. 241: 103–109. 60 Dourish, C. T., W. Rycroft & S. D. Iversen. 1989. Postponement of satiety by blockade of brain cholecystokinin (CCK-B) receptors. Science 245: 1509–1511. 61 Weller, A., G. P. Smith & J. Gibbs. 1990. Endogenous cholecystokinin reduces feeding in young rats. Science 247: 1589–1591. 62 Reidelberger, R., G. Varga & T. E. Solomon. 1991. Effects of selective cholecystokinin antagonists L364,718 and L365,260 on food intake in rats. Peptides 12: 1215–1221. 63 Schick, R. R., V. Schusdziarra, C. Endres, T. Eberl & M. Classen. 1991. Putative sleep factors and satiety in rats: Role of cholecystokinin (CCK) and delta sleep inducing peptide (DSIP). Neuropeptides (Life Sci. Adv.) 10: 41–48. 64 Zarbin, M. S., J. K. Wamsley, R. B. Innis & M. J. Kuhar. 1981. Cholecystokinin receptors: Presence and axonal flow in the rat vagus nerve. Life Sci. 29: 697–705. 65 Palkovits, M., J. Z. Kiss, M. C. Beinfeld & T. H. Williams. 1982. Cholecystokinin in the nucleus of the solitary tract of the rat: Evidence for its vagal origin. Brain Res. 252: 386–390. 66 Inagaki, S., Y. Shiotani, M. Yamano, S. Shiosaka, H. Takagi, K. Tateishi, E. Hashimura, T. Hamaoka & M. Tohyama. 1984. Distribution, origin, and fine structures of cholecystokinin-8-like immunoreactive terminals in the nucleus ventromedialis hypothalami of the rat. J. Neurosci. 4: 1289–1299. 67 Crawley, J. 1985. Neurochemical investigation of the afferent pathway from the vagus nerve to the nucleus tractus solitarius in mediating the “satiety syndrome” induced by systemic cholecystokinin. Peptides 6 (Suppl. 1): 133–137. Citing Literature Volume713, Issue1CholecystokininMarch 1994Pages 242-254 ReferencesRelatedInformation