Artigo Revisado por pares

A model for the action of cereal alpha amylases on amylose

1985; Elsevier BV; Volume: 142; Issue: 2 Linguagem: Inglês

10.1016/0008-6215(85)85025-4

ISSN

1873-426X

Autores

E. Ann MacGregor, Alex W. MacGregor,

Tópico(s)

Phytase and its Applications

Resumo

A model is proposed to explain the action of cereal alpha amylases (EC 3.2.1.1) on such linear substrates as amylose. It is suggested that, at the active site of the enzyme, there are nine contiguous subsites, each capable of interacting with a glucose residue. An estimate is made of the energies involved in subsite-glucose interaction, and values obtained for the binding energies are used to predict the distributions of small oligosaccharides to be expected at intermediate stages of amylose hydrolysis catalyzed by cereal alpha amylases.

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