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Proximo-Distal Movement along the Axon of Protein synthesized in the Perikaryon of Regenerating Neurons

1960; Nature Portfolio; Volume: 185; Issue: 4712 Linguagem: Inglês

10.1038/185541a0

1476-4687

N. Miani,

Nerve injury and regeneration

DURING regeneration of crushed nerve-fibres of spinal ganglion cells, the turnover rate of proteins in the ganglia (C.7 and C.8) increases extensively, as compared with the controls1. This finding, on one hand, justifies the increase in protein in the perikaryon of the regenerating neuron1,2; on the other hand, it supports Weiss's opinion3 that some of the new proteins leave the body-cell and reach the growing end of the axon.