Selective Activation of Alkyl– and Aryl–Oxygen Single Bonds in Solution with Transition Metal Complexes
1997; Wiley; Volume: 36; Issue: 6 Linguagem: Inglês
10.1002/anie.199706251
ISSN1521-3773
AutoresMilko E. van der Boom, Shyh‐Yeon Liou, Yehoshoa Ben‐David, Arkadi Vigalok, David Milstein,
Tópico(s)Asymmetric Synthesis and Catalysis
ResumoAn unprecedented metal insertion into the strong sp2sp3 arylO bond to form 2 is observed for the reaction of [{RhCl(C8H14)2}2] (C8H14 = cyclooctene) with two equivalents of the aryl ether phosphane 1. This reaction proceeds directly, even at room temperature, with no rhodium insertion into the adjacent weaker ArOCH3 bond. However, the alkylO bond is activated by the reaction of 1 with [Pd-(CF3CO2)2] to give 3. Selectivity of CO activation can therefore be directed by choice of metal complex.
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