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Cancer detection using nanoparticle-based sensors

2011; Royal Society of Chemistry; Volume: 41; Issue: 7 Linguagem: Inglês

10.1039/c1cs15134g

1460-4744

Maëlle Perfézou, Anthony Turner, Arben Merkoçi,

Advanced Biosensing Techniques and Applications

This tutorial review surveys the latest achievements in the use of nanoparticles to detect cancer biomarkers and cancer cells with a focus on optical and electrochemical techniques. Nanoparticle based cancer diagnostics are becoming an increasingly relevant alternative to traditional techniques. Although some drawbacks exist in relation to the obtained sensitivity the use of nanoparticle-based sensors in biomarker detection or cancer cell detection offers some advantages in comparison to conventional methods. The developed techniques can be interesting and relevant for their use in point-of-care of cancer diagnostics. The methods can be of low cost and in addition easy to be incorporated into user-friendly sensing platforms.