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Pilo-sebaceous duct physiology. I EFFECT OF HYDRATION ON PILO-SEBACEOUS DUCT ORIFICE

1974; Oxford University Press; Volume: 90; Issue: 6 Linguagem: Inglês

10.1111/j.1365-2133.1974.tb06691.x

1365-2133

Margaret Williams, W.J. Cunliffe, David Gould,

Acne and Rosacea Treatments and Effects

British Journal of DermatologyVolume 90, Issue 6 p. 631-635 Pilo-sebaceous duct physiology. I EFFECT OF HYDRATION ON PILO-SEBACEOUS DUCT ORIFICE M. WILLIAMS, M. WILLIAMS The Departments of Dermatology, The General Infirmary, Leeds, and Leeds (St James's) University HospitalSearch for more papers by this authorW.J. CUNLIFFE, W.J. CUNLIFFE The Departments of Dermatology, The General Infirmary, Leeds, and Leeds (St James's) University HospitalSearch for more papers by this authorD. GOULD, D. GOULD The Departments of Dermatology, The General Infirmary, Leeds, and Leeds (St James's) University HospitalSearch for more papers by this author M. WILLIAMS, M. WILLIAMS The Departments of Dermatology, The General Infirmary, Leeds, and Leeds (St James's) University HospitalSearch for more papers by this authorW.J. CUNLIFFE, W.J. CUNLIFFE The Departments of Dermatology, The General Infirmary, Leeds, and Leeds (St James's) University HospitalSearch for more papers by this authorD. GOULD, D. GOULD The Departments of Dermatology, The General Infirmary, Leeds, and Leeds (St James's) University HospitalSearch for more papers by this author First published: June 1974 https://doi.org/10.1111/j.1365-2133.1974.tb06691.xCitations: 28AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat SUMMARY Using a surface microscope technique to measure the pilo-sebaceous duct orifices in vivo, it has been shown that keratin hydration, as produced either by a hot bath or by polythene occlusion, decreases the pilo-sebaceous orifice size. These changes arc reversed within 90 min. This reduction in pilo-sebaceous duct orifice size would increase sebum outflow resistance and aggravate duct obstruction. The observations therefore help to explain the exacerbation of acne seen in humid environments, such as in the tropics, and in certain occupations. Citing Literature Volume90, Issue6June 1974Pages 631-635 RelatedInformation