Portal de Periódicos da CAPES

FSH in therapy: physiological basis, new preparations and clinical use

1995; Cambridge University Press; Volume: 4; Issue: 3 Linguagem: Inglês

10.1017/s0962279900001150

1469-9028

Manuela Simoni, Eberhard Nieschlag,

Reproductive Biology and Fertility

Follicle stimulating hormone (FSH) is a glycoprotein hormone secreted by the pituitary gland that, together with luteinizing hormone (LH), controls development, maturation and function of the gonad. Like the related hormones, LH, thyroid stimulating hormone (TSH) and human chorionic gonadotropin (hCG), FSH consists of two polypeptide chains, α and β, bearing carbohydrate moieties N -linked to asparagine (Asn) residues. The α subunit is common to all members of the glycoprotein hormone family, whereas the β subunit, although structurally very similar, differs in each hormone and confers specificity of action.