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New HA 14-1 analogues: synthesis of 2-amino-4-cyano-4H-chromenes

2010; Elsevier BV; Volume: 51; Issue: 48 Linguagem: Inglês

10.1016/j.tetlet.2010.09.090

1873-3581

Leila Moafi, Somayeh Ahadi, Ayoob Bazgir,

Synthesis and biological activity

The synthesis of 2-amino-4-cyano-4H-chromene derivatives as new HA 14-1 analogues by a simple and efficient method is reported. In addition, the reaction of 2-amino-2H-chromene-3-carbonitriles, salicylaldehydes and amines results in the formation of new chromeno[2,3-d]pyrimidine derivatives.