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Late gadolinium enhanced cardiovascular magnetic resonance of lamin A/C gene mutation related dilated cardiomyopathy

2011; BioMed Central; Volume: 13; Issue: 1 Linguagem: Inglês

10.1186/1532-429x-13-30

1532-429X

Miia Holmström, Sari Kivistö, Tiina Heliö, Raija Jurkko, Maija Kaartinen, Margareta Antila, Eeva Reissell, Johanna Kuusisto, Satu Kärkkäinen, Keijo Peuhkurinen, Juha Koikkalainen, Jyrki Lötjönen, Kirsi Lauerma,

RNA Research and Splicing

The purpose of this study was to identify early features of lamin A/C gene mutation related dilated cardiomyopathy (DCM) with cardiovascular magnetic resonance (CMR). We characterise myocardial and functional findings in carriers of lamin A/C mutation to facilitate the recognition of these patients using this method. We also investigated the connection between myocardial fibrosis and conduction abnormalities.